In situ hybridization for Cytokines in human tissue biopsy. Responsibility: edited by Patricia J. Emily Mathey is a postdoctoral scientist at the Brain and Mind Research Institute at the University of Sydney. Comparative biology of Schwann cells and oligodendrocytes Rudolf Martini, Janos Groh and Udo Bartsch; 3. European Neurological Review, 8 1 , 51-56. Nielsen, Pierre Lau and Lynn D. Muscle and Nerve, 57 5 , 848-851.
Proceedings of the National Academy of Sciences of the United States of America, 106 20 , 8302-8307. Autoantibody responses to nodal and paranodal antigens in chronic inflammatory neuropathies. San Diego: Peripheral Nerve Society. Written like a scientific review article with an extensive introduction at the start of every individual section, the book covers such diverse topics as the development of the study of oligodendrocytes, comparative biology of oligodendrocytes and Schwann cells, the development of oligodendrocytes and vertebral myelination, immunology of oligodendrocytes, and the dynamics of oligodendrocyte progenitor cells in aging nervous systems, while maintaining focus on myelin disease and injury. Emily Mathey is a postdoctoral scientist at the Brain and Mind Research Institute at the University of Sydney. Later chapters explore the role that damage to these often overlooked cells plays in diseases of the central nervous system, with a particular focus on multiple sclerosis. Neurofascin-155 IgG4 Neuropathy: Pathophysiological insights, spectrum of clinical severity and response to treatment.
Axon damage in central nervous system and peripheral nervous system inflammatory demyelinating diseases: common and divergent pathways of dysfunction and tissue damage. Molecular organization of the oligodendrocyte and myelin Grahame Kidd and Bruce D. The Biology Of Oligodendrocytes Armati Patricia Mathey Emily can be very useful guide, and the biology of oligodendrocytes armati patricia mathey emily play an important role in your products. Journal of Neurology, Neurosurgery and Psychiatry, 86 9 , 973-985. Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype.
Journal of Neuroimmunology, 309, 41-46. Patricia Armati is Associate Professor of Neuroscience and co-director of the Nerve Research Foundation, Brain and Mind Research Institute at the University of Sydney, Australia. New Treatments for Chronic Inflammatory Demyelinating Polyneuropathy. Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. Journal of the Peripheral Nervous System, 19 1 , 14-23. Muscle and Nerve, 57 5 , 848-851. Immunobiology of the oligodendrocyte David Kremer, Orhan Aktas, Hans-Peter Hartung and Patrick Kury; 7.
In addition, the book, to its credit, devotes almost equal time to the discussion of spontaneous myelin regeneration and the potential ways in which myelination can be induced, either through drugs or through transplantation of either oligodendrocytes or their associated progenitor cells. Neurofascin as a novel target for autoantibody-mediated axonal injury. The genetics of oligodendrocytes Joseph A. Patricia Armati is Associate Professor of Neuroscience and co-director of the Nerve Research Foundation, Brain and Mind Research Institute at the University of Sydney, Australia. In Marc de Lay Eds. Nielsen, Pierre Lau and Lynn D.
The book also effectively outlines the potential of, and problems with, oligodendrocytes as therapeutic targets in spinal cord injury by extensively covering the cellular biology of oligodendrocytes down to specific ion concentrations. Neurology: Neuroimmunology and Neuroinflammation, 2014 1 , 1-10. She has a keen interest in both immunology and neurobiology with particular emphasis on pathogenic antibody responses in demyelinating disease of the peripheral and central nervous systems. The myelin formed by the two glial cell types electrically insulates the axons and restricts the generation of action potentials to the nodes of Ranvier, myelin-free regions separating the myelin segments, allowing for rapid propagation of actions potentials along the axons. The Journal of Experimental Medicine, 204 10 , 2363-2372.
Journal of Neuroimmunology, 116, 226-232. The occasional diagram greatly facilitates the communication of concepts, specifically the degeneration of the myelin sheath and differentiation of oligodendrocytes, as well as differences between myelin degradation as a result of trauma, injury, or multiple sclerosis, though the diagrams are few and far between. She has a long standing interest in the cells of the nervous system and the relationship to disease and is editor of The Biology of Schwann Cells Cambridge University Press, 2007. Unlike other sections, however, the section on the molecular basis of demyelination is almost entirely unknown. Journal of Neuroimmunology, 277 1-2 , 13-17. Clinical Neurophysiology, 129 10 , 2162-2169. Glutamate receptors, transporters, and periventricular leukomalacia Tara M.
Motor unit remodelling in multifocal motor neuropathy: The importance of axonal loss. When the subject under discussion extends beyond our current understanding of neuroscience, this fact is mentioned explicitly and the most applicable ongoing study is mentioned for the reader's further review, which I found to be extraordinarily valuable as I often felt the need to consult reference material while reading. An update on Schwann cell biology - Immunomodulation, neural regulation and other surprises. Journal of Neurology, Neurosurgery and Psychiatry, 86 9 , 973-985. Immunobiology of the oligodendrocyte David Kremer, Orhan Aktas, Hans-Peter Hartung and Patrick Küry; 7. The molecular basis of demyelination, like most other topics covered by the book, is covered in extreme, bordering on tedious, detail.
If you do not have any background in neuroscience or cellular biology, and are still interested in reading this book, I recommend that you have a plethora of reference material immediately available to you as this book can get very technical very fast. In Hugh J Willison, John A Goodfellow Eds. Autoantibody responses to nodal and paranodal antigens in chronic inflammatory neuropathies. This is the first dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics and immunobiology. Antibodies to neurofascin exacerbate adoptive transfer experimental autoimmune neuritis. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology.
The rise of the oligodendrocyte in a neuron-centric culture Emily Mathey, Ariel Arthur and Patricia Armati; 2. The molecular basis of myelin disease and injury is impeccably well described and extremely detailed though the emphasis on diseased states can lead to some confusion at least this was the case for me. New Treatments for Chronic Inflammatory Demyelinating Polyneuropathy. Later chapters explore the role that damage to these often overlooked cells plays in diseases of the central nervous system, with a particular focus on multiple sclerosis. The ethical issues are only raised, and no concrete solutions are offered.